Estimation of Cell-Type Composition Including T and B Cell Subtypes for Whole Blood Methylation Microarray Data

DNA methylation levels vary markedly by cell-type makeup of a sample. Understanding these differences and estimating the cell-type makeup of a sample is an important aspect of studying DNA methylation. DNA from leukocytes in whole blood is simple to obtain and pervasive in research. However, leukocy...

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Detalles Bibliográficos
Publicado en:Front Genet
Main Authors: Waite, Lindsay L., Weaver, Benjamin, Day, Kenneth, Li, Xinrui, Roberts, Kevin, Gibson, Andrew W., Edberg, Jeffrey C., Kimberly, Robert P., Absher, Devin M., Tiwari, Hemant K.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2016
Assuntos:
Genetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757643/
https://ncbi.nlm.nih.gov/pubmed/26925097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00023
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