Lubiprostone Reverses the Inhibitory Action of Morphine on Mucosal Secretion in Human Small Intestine

BACKGROUND AND AIMS: Treatments with morphine or opioid agonists cause constipation. Lubiprostone is approved for treatment of adult idiopathic constipation and constipation-predominant IBS in adult women. We tested whether lubiprostone can reverse morphine-suppression of mucosal secretion in human...

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Publicado en:Dig Dis Sci
Autores principales: Sun, Xiaohong, Wang, Xiyu, Wang, Guo-Du, Xia, Yun, Liu, Sumei, Qu, Meihua, Needleman, Bradley J., Mikami, Dean J., Melvin, W. Scott, Bohn, Laura M., Ueno, Ryuji, Wood, Jackie D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757489/
https://ncbi.nlm.nih.gov/pubmed/21181441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-010-1515-8
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