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tRNA is a new target for cleavage by a MazF toxin

Toxin-antitoxin (TA) systems play key roles in bacterial persistence, biofilm formation and stress responses. The MazF toxin from the Escherichia coli mazEF TA system is a sequence- and single-strand-specific endoribonuclease, and many studies have led to the proposal that MazF family members exclus...

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Publicat a:Nucleic Acids Res
Autors principals: Schifano, Jason M., Cruz, Jonathan W., Vvedenskaya, Irina O., Edifor, Regina, Ouyang, Ming, Husson, Robert N., Nickels, Bryce E., Woychik, Nancy A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756823/
https://ncbi.nlm.nih.gov/pubmed/26740583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1370
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