FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver

The liver is an important integrator of nutrient metabolism, yet no liver-derived factors regulating nutrient preference or carbohydrate appetite have been identified. Here we show that the liver regulates carbohydrate intake through production of the hepatokine fibroblast growth factor 21 (FGF21),...

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Pubblicato in:Cell Metab
Autori principali: von Holstein-Rathlou, Stephanie, BonDurant, Lucas, Peltekian, Lila, Naber, Meghan C., Yin, Terry C., Claflin, Kristin E., Urizar, Adriana Ibarra, Madsen, Andreas N., Ratner, Cecilia, Holst, Birgitte, Karstoft, Kristian, Vandenbeuch, Aurelie, Anderson, Catherine B., Cassell, Martin D., Thompson, Anthony P., Solomon, Thomas P. J., Rahmouni, Kamal, Kinnamon, Sue C., Pieper, Andrew A., Gillum, Matthew P., Potthoff, Matthew J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756759/
https://ncbi.nlm.nih.gov/pubmed/26724858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.12.003
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