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Three-dimensional spherical spatial boundary conditions differentially regulate osteogenic differentiation of mesenchymal stromal cells

The spatial boundary condition (SBC) arising from the surrounding microenvironment imposes specific geometry and spatial constraints that affect organogenesis and tissue homeostasis. Mesenchymal stromal cells (MSCs) sensitively respond to alterations of mechanical cues generated from the SBC. Howeve...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lo, Yin-Ping, Liu, Yi-Shiuan, Rimando, Marilyn G., Ho, Jennifer Hui-Chun, Lin, Keng-hui, Lee, Oscar K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756701/
https://ncbi.nlm.nih.gov/pubmed/26884253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21253
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