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Long-term safety and stability of angiogenesis induced by balanced single-vector co-expression of PDGF-BB and VEGF(164) in skeletal muscle
Therapeutic angiogenesis by growth factor delivery is an attractive treatment strategy for ischemic diseases, yet clinical efficacy has been elusive. The angiogenic master regulator VEGF-A can induce aberrant angiogenesis if expressed above a threshold level. Since VEGF remains localized in the matr...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4756385/ https://ncbi.nlm.nih.gov/pubmed/26882992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21546 |
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