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Bias-corrected targeted next-generation sequencing for rapid, multiplexed detection of actionable alterations in cell-free DNA from advanced lung cancer patients

PURPOSE: Tumor genotyping is a powerful tool for guiding non-small cell lung cancer (NSCLC) care, however comprehensive tumor genotyping can be logistically cumbersome. To facilitate genotyping, we developed a next-generation sequencing (NGS) assay using a desktop sequencer to detect actionable muta...

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Detaylı Bibliyografya
Yayımlandı:Clin Cancer Res
Asıl Yazarlar: Paweletz, Cloud P., Sacher, Adrian G., Raymond, Chris K., Alden, Ryan S., O'Connell, Allison, Mach, Stacy L., Kuang, Yanan, Gandhi, Leena, Kirschmeier, Paul, English, Jessie M., Lim, Lee P., Jänne, Pasi A., Oxnard, Geoffrey R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755822/
https://ncbi.nlm.nih.gov/pubmed/26459174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1627-T
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