Bias-corrected targeted next-generation sequencing for rapid, multiplexed detection of actionable alterations in cell-free DNA from advanced lung cancer patients

PURPOSE: Tumor genotyping is a powerful tool for guiding non-small cell lung cancer (NSCLC) care, however comprehensive tumor genotyping can be logistically cumbersome. To facilitate genotyping, we developed a next-generation sequencing (NGS) assay using a desktop sequencer to detect actionable muta...

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Bibliografiska uppgifter
I publikationen:Clin Cancer Res
Huvudupphovsmän: Paweletz, Cloud P., Sacher, Adrian G., Raymond, Chris K., Alden, Ryan S., O'Connell, Allison, Mach, Stacy L., Kuang, Yanan, Gandhi, Leena, Kirschmeier, Paul, English, Jessie M., Lim, Lee P., Jänne, Pasi A., Oxnard, Geoffrey R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755822/
https://ncbi.nlm.nih.gov/pubmed/26459174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1627-T
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