Bias-corrected targeted next-generation sequencing for rapid, multiplexed detection of actionable alterations in cell-free DNA from advanced lung cancer patients

PURPOSE: Tumor genotyping is a powerful tool for guiding non-small cell lung cancer (NSCLC) care, however comprehensive tumor genotyping can be logistically cumbersome. To facilitate genotyping, we developed a next-generation sequencing (NGS) assay using a desktop sequencer to detect actionable muta...

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Pubblicato in:Clin Cancer Res
Autori principali: Paweletz, Cloud P., Sacher, Adrian G., Raymond, Chris K., Alden, Ryan S., O'Connell, Allison, Mach, Stacy L., Kuang, Yanan, Gandhi, Leena, Kirschmeier, Paul, English, Jessie M., Lim, Lee P., Jänne, Pasi A., Oxnard, Geoffrey R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755822/
https://ncbi.nlm.nih.gov/pubmed/26459174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1627-T
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