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Bias-corrected targeted next-generation sequencing for rapid, multiplexed detection of actionable alterations in cell-free DNA from advanced lung cancer patients

PURPOSE: Tumor genotyping is a powerful tool for guiding non-small cell lung cancer (NSCLC) care, however comprehensive tumor genotyping can be logistically cumbersome. To facilitate genotyping, we developed a next-generation sequencing (NGS) assay using a desktop sequencer to detect actionable muta...

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Detalles Bibliográficos
Publicado en:Clin Cancer Res
Main Authors: Paweletz, Cloud P., Sacher, Adrian G., Raymond, Chris K., Alden, Ryan S., O'Connell, Allison, Mach, Stacy L., Kuang, Yanan, Gandhi, Leena, Kirschmeier, Paul, English, Jessie M., Lim, Lee P., Jänne, Pasi A., Oxnard, Geoffrey R.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755822/
https://ncbi.nlm.nih.gov/pubmed/26459174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1627-T
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