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Multinucleation and Mesenchymal-to-Epithelial-Transition Alleviate Resistance to Combined Cabazitaxel and Antiandrogen Therapy in Advanced Prostate Cancer

Patients with metastatic castration resistant prostate cancer (mCRPC) frequently develop therapeutic resistance to taxane chemotherapy and antiandrogens. Cabazitaxel (CBZ) is a second-line taxane chemotherapeutic agent that provides additional survival benefits to patients with advanced disease. In...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Martin, Sarah K., Pu, Hong, Penticuff, Justin C., Cao, Zheng, Horbinski, Craig, Kyprianou, Natasha
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755804/
https://ncbi.nlm.nih.gov/pubmed/26645563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2078
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