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Multinucleation and Mesenchymal-to-Epithelial-Transition Alleviate Resistance to Combined Cabazitaxel and Antiandrogen Therapy in Advanced Prostate Cancer

Patients with metastatic castration resistant prostate cancer (mCRPC) frequently develop therapeutic resistance to taxane chemotherapy and antiandrogens. Cabazitaxel (CBZ) is a second-line taxane chemotherapeutic agent that provides additional survival benefits to patients with advanced disease. In...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Martin, Sarah K., Pu, Hong, Penticuff, Justin C., Cao, Zheng, Horbinski, Craig, Kyprianou, Natasha
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755804/
https://ncbi.nlm.nih.gov/pubmed/26645563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2078
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