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ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization

Dynamic changes in protein S-palmitoylation are critical for regulating protein localization and signaling. Only two enzymes - the acyl-protein thioesterases APT1 and APT2 – are known to catalyze palmitate removal from cytosolic cysteine residues. It is unclear if these enzymes act constitutively on...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Lin, David Tse Shen, Conibear, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755737/
https://ncbi.nlm.nih.gov/pubmed/26701913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11306
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