Altered Energetics of Exercise Explain Risk of Rhabdomyolysis in Very Long-Chain Acyl-CoA Dehydrogenase Deficiency

Rhabdomyolysis is common in very long-chain acyl-CoA dehydrogenase deficiency (VLCADD) and other metabolic myopathies, but its pathogenic basis is poorly understood. Here, we show that prolonged bicycling exercise against a standardized moderate workload in VLCADD patients is associated with threefo...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Diekman, E. F., Visser, G., Schmitz, J. P. J., Nievelstein, R. A. J., de Sain-van der Velden, M., Wardrop, M., Van der Pol, W. L., Houten, S. M., van Riel, N. A. W., Takken, T., Jeneson, J. A. L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755596/
https://ncbi.nlm.nih.gov/pubmed/26881790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147818
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