Constructing a linkage–linkage disequilibrium map using dominant-segregating markers

The relationship between linkage disequilibrium (LD) and recombination fraction can be used to infer the pattern of genetic variation and evolutionary process in humans and other systems. We described a computational framework to construct a linkage–LD map from commonly used biallelic, single-nucleo...

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Publicado en:DNA Res
Autores principales: Zhu, Xuli, Dong, Leiming, Jiang, Libo, Li, Huan, Sun, Lidan, Zhang, Hui, Yu, Weiwu, Liu, Haokai, Dai, Wensheng, Zeng, Yanru, Wu, Rongling
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755522/
https://ncbi.nlm.nih.gov/pubmed/26622063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/dnares/dsv031
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