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Mouse models of colorectal cancer as preclinical models

In this review, we discuss the application of mouse models to the identification and pre‐clinical validation of novel therapeutic targets in colorectal cancer, and to the search for early disease biomarkers. Large‐scale genomic, transcriptomic and epigenomic profiling of colorectal carcinomas has le...

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Publicat a:Bioessays
Autors principals: McIntyre, Rebecca E., Buczacki, Simon J.A., Arends, Mark J., Adams, David J.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755199/
https://ncbi.nlm.nih.gov/pubmed/26115037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201500032
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