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Mouse models of colorectal cancer as preclinical models

In this review, we discuss the application of mouse models to the identification and pre‐clinical validation of novel therapeutic targets in colorectal cancer, and to the search for early disease biomarkers. Large‐scale genomic, transcriptomic and epigenomic profiling of colorectal carcinomas has le...

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Detalhes bibliográficos
Publicado no:Bioessays
Main Authors: McIntyre, Rebecca E., Buczacki, Simon J.A., Arends, Mark J., Adams, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755199/
https://ncbi.nlm.nih.gov/pubmed/26115037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201500032
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