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A single residue substitution accounts for the significant difference in thermostability between two isoforms of human cytosolic creatine kinase

Creatine kinase (CK) helps maintain homeostasis of intracellular ATP level by catalyzing the reversible phosphotransfer between ATP and phosphocreatine. In humans, there are two cytosolic CK isoforms, the muscle-type (M) and the brain-type (B), which frequently function as homodimers (hMMCK and hBBC...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Rep
मुख्य लेखकों: Liu, Huihui, Gao, Yan-Song, Chen, Xiang-Jun, Chen, Zhe, Zhou, Hai-Meng, Yan, Yong-Bin, Gong, Haipeng
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754747/
https://ncbi.nlm.nih.gov/pubmed/26879258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21191
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