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Cell contractility arising from topography and shear flow determines human mesenchymal stem cell fate

Extracellular matrix (ECM) of the human Mesenchymal Stem Cells (MSCs) influences intracellular tension and is known to regulate stem cell fate. However, little is known about the physiological conditions in the bone marrow, where external forces such as fluid shear stress, apart from the physical ch...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sonam, Surabhi, Sathe, Sharvari R., Yim, Evelyn K.F., Sheetz, Michael P., Lim, Chwee Teck
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754642/
https://ncbi.nlm.nih.gov/pubmed/26879739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20415
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