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Cell contractility arising from topography and shear flow determines human mesenchymal stem cell fate

Extracellular matrix (ECM) of the human Mesenchymal Stem Cells (MSCs) influences intracellular tension and is known to regulate stem cell fate. However, little is known about the physiological conditions in the bone marrow, where external forces such as fluid shear stress, apart from the physical ch...

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Foilsithe in:Sci Rep
Main Authors: Sonam, Surabhi, Sathe, Sharvari R., Yim, Evelyn K.F., Sheetz, Michael P., Lim, Chwee Teck
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754642/
https://ncbi.nlm.nih.gov/pubmed/26879739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20415
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