Development of Novel Adenoviral Vectors to Overcome Challenges Observed With HAdV-5–based Constructs

Recombinant vectors based on human adenovirus serotype 5 (HAdV-5) have been extensively studied in preclinical models and clinical trials over the past two decades. However, the thorough understanding of the HAdV-5 interaction with human subjects has uncovered major concerns about its product applic...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Ther
Auteurs principaux: Alonso-Padilla, Julio, Papp, Tibor, Kaján, Győző L, Benkő, Mária, Havenga, Menzo, Lemckert, Angelique, Harrach, Balázs, Baker, Andrew H
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754553/
https://ncbi.nlm.nih.gov/pubmed/26478249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.194
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