Yüklüyor......
Myocardial Delivery of Lipidoid Nanoparticle Carrying modRNA Induces Rapid and Transient Expression
Nanoparticle-based delivery of nucleotides offers an alternative to viral vectors for gene therapy. We report highly efficient in vivo delivery of modified mRNA (modRNA) to rat and pig myocardium using formulated lipidoid nanoparticles (FLNP). Direct myocardial injection of FLNP containing 1–10 μg e...
Kaydedildi:
| Yayımlandı: | Mol Ther |
|---|---|
| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2016
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4754552/ https://ncbi.nlm.nih.gov/pubmed/26471463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.193 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|