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Molecular mechanisms underlying RB protein function

Inactivation of the RB protein is one of the most fundamental events in cancer. Coming to a molecular understanding of its function in normal cells and how it impedes cancer development has been challenging. Historically, the ability of RB to regulate the cell cycle placed it in a central role in pr...

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Detalhes bibliográficos
Publicado no:Nat Rev Mol Cell Biol
Main Authors: Dick, Frederick A., Rubin, Seth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754300/
https://ncbi.nlm.nih.gov/pubmed/23594950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3567
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