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Molecular mechanisms underlying the enhanced functions of three-dimensional hepatocyte aggregates
Three-dimensional (3D) culture of hepatocytes leads to improved and prolonged synthetic and metabolic functions, but the underlying molecular mechanisms are unknown. In order to investigate the role of 3D cell-cell interactions in maintaining hepatocyte differentiated functions ex vivo, primary mous...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4012541/ https://ncbi.nlm.nih.gov/pubmed/24332390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.11.063 |
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