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Pseudomonas aeruginosa stimulates tyrosine phosphorylation of and TLR5 association with the MUC1 cytoplamic tail through EGFR activation

BACKGROUND: MUC1 is a membrane-tethered mucin expressed on the surface of epithelial and hematopoietic cells. Previous studies have established that MUC1 attenuates airway inflammation in response to Pseudomonas aeruginosa (Pa) through suppression of Toll-like receptor (TLR) signaling. Here, we eluc...

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Detalhes bibliográficos
Publicado no:Inflamm Res
Main Authors: Kato, Kosuke, Lillehoj, Erik P., Kim, Kwang Chul
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754158/
https://ncbi.nlm.nih.gov/pubmed/26645913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-015-0908-8
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