Pseudomonas aeruginosa Increases MUC1 Expression in Macrophages Through the TLR4-p38 Pathway

Alveolar macrophages (AMs) play a critical role in the clearance of Pseudomonas aeruginosa (Pa) from the airways. However, hyper-activation of macrophages can impair bacterial clearance and contribute to morbidity and mortality. MUC1 mucin is a membrane-tethered, high molecular mass glycoprotein exp...

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Détails bibliographiques
Publié dans:Biochem Biophys Res Commun
Auteurs principaux: Kato, Kosuke, Hanss, Alec D., Zemskova, Marina A, Morgan, Nicole E., Kim, Marianne, Knox, Kenneth S., Lin, Yong, Lillehoj, Erik. P., Kim, Kwang Chul
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599168/
https://ncbi.nlm.nih.gov/pubmed/28822766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.08.056
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