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Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics

Induced pluripotent stem cell (iPSC)-derived cortical neurons potentially present a powerful new model to understand corticogenesis and neurological disease. Previous work has established that differentiation protocols can produce cortical neurons, but little has been done to characterize these at c...

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Библиографические подробности
Опубликовано в: :Hum Mol Genet
Главные авторы: Handel, Adam E., Chintawar, Satyan, Lalic, Tatjana, Whiteley, Emma, Vowles, Jane, Giustacchini, Alice, Argoud, Karene, Sopp, Paul, Nakanishi, Mahito, Bowden, Rory, Cowley, Sally, Newey, Sarah, Akerman, Colin, Ponting, Chris P., Cader, M. Zameel
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754051/
https://ncbi.nlm.nih.gov/pubmed/26740550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv637
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