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Activation of microglial P2Y12 receptor is required for outward potassium currents in response to neuronal injury

Microglia, the resident immune cells in the central nervous system, constantly survey the surrounding neural parenchyma and promptly respond to brain injury. Activation of purinergic receptors such as P2Y12 receptors (P2Y12R) in microglia has been implicated in chemotaxis towards ATP that is release...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuroscience
Prif Awduron: Swiatkowski, Przemyslaw, Murugan, Madhuvika, Eyo, Ukpong B., Wang, Yuanyin, Rangaraju, Srikant, Oh, Seog Bae, Wu, Long-Jun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753827/
https://ncbi.nlm.nih.gov/pubmed/26791526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.01.008
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