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Activation of microglial P2Y12 receptor is required for outward potassium currents in response to neuronal injury

Microglia, the resident immune cells in the central nervous system, constantly survey the surrounding neural parenchyma and promptly respond to brain injury. Activation of purinergic receptors such as P2Y12 receptors (P2Y12R) in microglia has been implicated in chemotaxis towards ATP that is release...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: Swiatkowski, Przemyslaw, Murugan, Madhuvika, Eyo, Ukpong B., Wang, Yuanyin, Rangaraju, Srikant, Oh, Seog Bae, Wu, Long-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753827/
https://ncbi.nlm.nih.gov/pubmed/26791526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.01.008
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