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Decorin as a multivalent therapeutic agent against cancer
Decorin is a prototypical small leucine-rich proteoglycan and epitomizes the multifunctional nature of this critical gene family. Soluble decorin engages multiple receptor tyrosine kinases within the target rich environment of the tumor stroma and tumor parenchyma. Upon receptor binding, decorin ini...
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| Udgivet i: | Adv Drug Deliv Rev |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4753134/ https://ncbi.nlm.nih.gov/pubmed/26522384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2015.10.016 |
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