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Decorin as a multivalent therapeutic agent against cancer

Decorin is a prototypical small leucine-rich proteoglycan and epitomizes the multifunctional nature of this critical gene family. Soluble decorin engages multiple receptor tyrosine kinases within the target rich environment of the tumor stroma and tumor parenchyma. Upon receptor binding, decorin ini...

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Dades bibliogràfiques
Publicat a:Adv Drug Deliv Rev
Autors principals: Neill, Thomas, Schaefer, Liliana, Iozzo, Renato V.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753134/
https://ncbi.nlm.nih.gov/pubmed/26522384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2015.10.016
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