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Genome Neighborhood Network Reveals Insights into Enediyne Biosynthesis and Facilitates Prediction and Prioritization for Discovery

The enediynes are one of the most fascinating families of bacterial natural products given their unprecedented molecular architecture and extraordinary cytotoxicity. Enediynes are rare with only 11 structurally characterized members and four additional members isolated in their cycloaromatized form....

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Vydáno v:J Ind Microbiol Biotechnol
Hlavní autoři: Rudolf, Jeffrey D., Yan, Xiaohui, Shen, Ben
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753101/
https://ncbi.nlm.nih.gov/pubmed/26318027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10295-015-1671-0
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