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Asymmetric Modulation of Protein Order-Disorder Transitions by Phosphorylation and Partner Binding()
As for many intrinsically disordered proteins, order-disorder transitions in the N-terminal oligomerization domain of the multi-functional nucleolar protein, nucleophosmin (Npm-N) are central to its function, with phosphorylation and partner-binding acting as regulatory switches. However, the mechan...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4752826/ https://ncbi.nlm.nih.gov/pubmed/26679013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201507728 |
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