Why it is crucial to analyze non clonal chromosome aberrations or NCCAs?

Current cytogenetics has largely focused its efforts on the identification of recurrent karyotypic alterations, also known as clonal chromosomal aberrations (CCAs). The rationale of doing so seems simple: recurrent genetic changes are relevant for diseases or specific physiological conditions, while...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cytogenet
Main Authors: Heng, Henry H. Q., Regan, Sarah M., Liu, Guo, Ye, Christine J.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Commentary
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752783/
https://ncbi.nlm.nih.gov/pubmed/26877768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-016-0223-2
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