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Why it is crucial to analyze non clonal chromosome aberrations or NCCAs?

Current cytogenetics has largely focused its efforts on the identification of recurrent karyotypic alterations, also known as clonal chromosomal aberrations (CCAs). The rationale of doing so seems simple: recurrent genetic changes are relevant for diseases or specific physiological conditions, while...

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Detalhes bibliográficos
Publicado no:Mol Cytogenet
Main Authors: Heng, Henry H. Q., Regan, Sarah M., Liu, Guo, Ye, Christine J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752783/
https://ncbi.nlm.nih.gov/pubmed/26877768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-016-0223-2
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