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RECQ helicases are deregulated in hematological malignancies in association with a prognostic value

BACKGROUND: RECQ helicase family members act as guardians of the genome to assure proper DNA metabolism in response to genotoxic stress. Hematological malignancies are characterized by genomic instability that is possibly related to underlying defects in DNA repair of genomic stability maintenance....

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Detalhes bibliográficos
Publicado no:Biomark Res
Main Authors: Viziteu, Elena, Kassambara, Alboukadel, Pasero, Philippe, Klein, Bernard, Moreaux, Jerome
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752763/
https://ncbi.nlm.nih.gov/pubmed/26877874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-016-0057-4
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