Methotrexate-mediated activation of an AMPK-CREB-dependent pathway: a novel mechanism for vascular protection in chronic systemic inflammation

AIMS: Premature cardiovascular events complicate chronic inflammatory conditions. Low-dose weekly methotrexate (MTX), the most widely used disease-modifying drug for rheumatoid arthritis (RA), reduces disease-associated cardiovascular mortality. MTX increases intracellular accumulation of adenosine...

全面介紹

Na minha lista:
書目詳細資料
發表在:Ann Rheum Dis
Main Authors: Thornton, C C, Al-Rashed, F, Calay, D, Birdsey, G M, Bauer, A, Mylroie, H, Morley, B J, Randi, A M, Haskard, D O, Boyle, J J, Mason, J C
格式: Artigo
語言:Inglês
出版: BMJ Publishing Group 2016
主題:
Basic and Translational Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752671/
https://ncbi.nlm.nih.gov/pubmed/25575725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2014-206305
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍