IL-6-driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anticitrullinated peptide antibody-negative rheumatoid arthritis

OBJECTIVES: A previously identified signal transduction and activator of transcription-3 (STAT3) target-enriched gene signature in circulating CD4+ T cells of patients with early rheumatoid arthritis (RA) was prominent in autoantibody-negative individuals. Here, interleukin (IL)-6-mediated STAT sign...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Anderson, Amy E, Pratt, Arthur G, Sedhom, Mamdouh A K, Doran, John Paul, Routledge, Christine, Hargreaves, Ben, Brown, Philip M, Lê Cao, Kim-Anh, Isaacs, John D, Thomas, Ranjeny
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
Assuntos:
Basic and Translational Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752669/
https://ncbi.nlm.nih.gov/pubmed/25649145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2014-205850
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