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Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway

Ebola virus (EBOV) makes extensive and intricate use of host factors in the cellular endosomal/lysosomal pathway to release its genome into the cytoplasm and initiate infection. Following viral internalization into endosomes, host cysteine proteases cleave the EBOV fusion glycoprotein (GP) to unmask...

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Publicado en:mBio
Main Authors: Spence, Jennifer S., Krause, Tyler B., Mittler, Eva, Jangra, Rohit K., Chandran, Kartik
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Microbiology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752599/
https://ncbi.nlm.nih.gov/pubmed/26861015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01857-15
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