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Concentration Sensing by the Moving Nucleus in Cell Fate Determination: A Computational Analysis

During development of the vertebrate neuroepithelium, the nucleus in neural progenitor cells (NPCs) moves from the apex toward the base and returns to the apex (called interkinetic nuclear migration) at which point the cell divides. The fate of the resulting daughter cells is thought to depend on th...

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Veröffentlicht in:PLoS One
Hauptverfasser: Aggarwal, Varun, Dickinson, Richard B., Lele, Tanmay P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752345/
https://ncbi.nlm.nih.gov/pubmed/26872214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149213
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