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Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade
Mechanical allodynia, induced by normally innocuous low-threshold mechanical stimulation, represents a cardinal feature of neuropathic pain. Blockade or ablation of high-threshold small-diameter unmyelinated C-fibers has limited effects on mechanical allodynia(1–4). While large myelinated A-fibers,...
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| Pubblicato in: | Nat Med |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4752254/ https://ncbi.nlm.nih.gov/pubmed/26479925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3978 |
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