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Study of force-induced melting of dsDNA as a function of length and conformation

We measure the constant force required to melt double-stranded DNA (ds) as a function of length for lengths from 12 to 100,000 base pairs, where the force is applied to the 3’3’ or 5’5’ ends of the dsDNA. Molecules with 32 base pairs or less melt before overstretching. For these short molecules, the...

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Publicado en:J Phys Condens Matter
Autores principales: Danilowicz, Claudia, Hatch, Kristi, Conover, Alyson, Ducas, Theodore, Gunaratne, Ruwan, Coljee, Vincent, Prentiss, Mara
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752207/
https://ncbi.nlm.nih.gov/pubmed/21386589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0953-8984/22/41/414106
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