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Study of force-induced melting of dsDNA as a function of length and conformation

We measure the constant force required to melt double-stranded DNA (ds) as a function of length for lengths from 12 to 100,000 base pairs, where the force is applied to the 3’3’ or 5’5’ ends of the dsDNA. Molecules with 32 base pairs or less melt before overstretching. For these short molecules, the...

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Detalhes bibliográficos
Publicado no:J Phys Condens Matter
Main Authors: Danilowicz, Claudia, Hatch, Kristi, Conover, Alyson, Ducas, Theodore, Gunaratne, Ruwan, Coljee, Vincent, Prentiss, Mara
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752207/
https://ncbi.nlm.nih.gov/pubmed/21386589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0953-8984/22/41/414106
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