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Solution-State (17)O Quadrupole Central Transition NMR Spectroscopy in the Active Site of Tryptophan Synthase

Oxygen is an essential participant in the acid-base chemistry that takes place within many enzyme active sites, yet has remained virtually silent as a probe in NMR spectroscopy. Here, we demonstrate the first use of solution-state (17)O quadrupole central transition NMR spectroscopy to characterize...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Angew Chem Int Ed Engl
Prif Awduron: Young, Robert P., Caulkins, Bethany G., Borchardt, Dan, Bulloch, Daryl N., Larive, Cynthia K., Dunn, Michael F., Mueller, Leonard J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752203/
https://ncbi.nlm.nih.gov/pubmed/26661504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201508898
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