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When Target:Decoy False Discovery Rate Estimations are Inaccurate and How to Spot Instances

To address problems with estimating the reliability of proteomic search engine results from mass spectrometry fragmentation data the use of target-decoy database searching has become the de facto approach for estimating a false discovery rate. Several articles have been written about the effects of...

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Vydáno v:J Proteome Res
Hlavní autor: Chalkley, Robert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751987/
https://ncbi.nlm.nih.gov/pubmed/23298186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr301063v
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