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Structural Similarities and Differences between Two Functionally Distinct SecA Proteins, Mycobacterium tuberculosis SecA1 and SecA2

While SecA is the ATPase component of the major bacterial secretory (Sec) system, mycobacteria and some Gram-positive pathogens have a second paralog, SecA2. In bacteria with two SecA paralogs, each SecA is functionally distinct, and they cannot compensate for one another. Compared to SecA1, SecA2 e...

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Bibliographische Detailangaben
Veröffentlicht in:J Bacteriol
Hauptverfasser: Swanson, Stephanie, Ioerger, Thomas R., Rigel, Nathan W., Miller, Brittany K., Braunstein, Miriam, Sacchettini, James C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751807/
https://ncbi.nlm.nih.gov/pubmed/26668263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00696-15
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