Mycobacterium tuberculosis SatS is a chaperone for the SecA2 protein export pathway

The SecA2 protein export system is critical for the virulence of Mycobacterium tuberculosis. However, the mechanism of this export pathway remains unclear. Through a screen for suppressors of a secA2 mutant, we identified a new player in the mycobacterial SecA2 pathway that we named SatS for SecA2 (...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Miller, Brittany K, Hughes, Ryan, Ligon, Lauren S, Rigel, Nathan W, Malik, Seidu, Anjuwon-Foster, Brandon R, Sacchettini, James C, Braunstein, Miriam
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2019
Fag:
Microbiology and Infectious Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333443/
https://ncbi.nlm.nih.gov/pubmed/30604681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40063
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