TGF-beta1 regulates human brain pericyte inflammatory processes involved in neurovasculature function

BACKGROUND: Transforming growth factor beta 1 (TGFβ(1)) is strongly induced following brain injury and polarises microglia to an anti-inflammatory phenotype. Augmentation of TGFβ(1) responses may therefore be beneficial in preventing inflammation in neurological disorders including stroke and neurod...

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Publicado en:J Neuroinflammation
Autores principales: Rustenhoven, Justin, Aalderink, Miranda, Scotter, Emma L., Oldfield, Robyn L., Bergin, Peter S., Mee, Edward W., Graham, E. Scott, Faull, Richard L. M., Curtis, Maurice A., Park, Thomas I-H., Dragunow, Mike
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751726/
https://ncbi.nlm.nih.gov/pubmed/26867675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0503-0
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