Interferon-γ blocks signalling through PDGFRβ in human brain pericytes

BACKGROUND: Neuroinflammation and blood-brain barrier (BBB) disruption are common features of many brain disorders, including Alzheimer’s disease, epilepsy, and motor neuron disease. Inflammation is thought to be a driver of BBB breakdown, but the underlying mechanisms for this are unclear. Brain pe...

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Bibliografische gegevens
Gepubliceerd in:J Neuroinflammation
Hoofdauteurs: Jansson, Deidre, Scotter, Emma L., Rustenhoven, Justin, Coppieters, Natacha, Smyth, Leon C. D., Oldfield, Robyn L., Bergin, Peter S., Mee, Edward W., Graham, E. Scott, Faull, Richard L. M., Dragunow, Mike
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031293/
https://ncbi.nlm.nih.gov/pubmed/27654972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0722-4
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