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APC binds the Miro/Milton motor complex to stimulate transport of mitochondria to the plasma membrane
Mutations in adenomatous polyposis coli (APC) disrupt regulation of Wnt signaling, mitosis, and the cytoskeleton. We describe a new role for APC in the transport of mitochondria. Silencing of wild-type APC by small interfering RNA caused mitochondria to redistribute from the cell periphery to the pe...
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| Pubblicato in: | Mol Biol Cell |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Cell Biology
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4751598/ https://ncbi.nlm.nih.gov/pubmed/26658612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-09-0632 |
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