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The language-related transcription factor FOXP2 is post-translationally modified with small ubiquitin-like modifiers

Mutations affecting the transcription factor FOXP2 cause a rare form of severe speech and language disorder. Although it is clear that sufficient FOXP2 expression is crucial for normal brain development, little is known about how this transcription factor is regulated. To investigate post-translatio...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Estruch, Sara B., Graham, Sarah A., Deriziotis, Pelagia, Fisher, Simon E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751435/
https://ncbi.nlm.nih.gov/pubmed/26867680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20911
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