Stalk-dependent and Stalk-independent Signaling by the Adhesion G Protein-coupled Receptors GPR56 (ADGRG1) and BAI1 (ADGRB1)

The adhesion G protein-coupled receptors (aGPCRs) are a large yet poorly understood family of seven-transmembrane proteins. A defining characteristic of the aGPCR family is the conserved GAIN domain, which has autoproteolytic activity and can cleave the receptors near the first transmembrane domain....

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Kishore, Ayush, Purcell, Ryan H., Nassiri-Toosi, Zahra, Hall, Randy A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751382/
https://ncbi.nlm.nih.gov/pubmed/26710850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.689349
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